The Role of ApoB in Cardiovascular Disease

Adequate risk assessment and management are crucial in preventing cardiovascular disease. A recent study examined the correlation between common measures of cholesterol concentration versus the number of apolipoprotein B (apo-B)-containing lipoproteins. In other words, should clinicians use different biomarkers for cardiovascular risk assessment? Cardiology Pharmacist, Lindsay Davis, joins Geoff Wall in this discussion.

The GameChanger 
Evidence is emerging to suggest apo-B is a more accurate biomarker of MI risk. While not routinely evaluated, apo-B is a GameChanger in that it can be helpful in determining cardiovascular risk in patients with borderline risk factors.  

 Show Segments 

00:00 – Introductions 
03:22 – Apolipoprotein B (apo-B) 
05:22 – Biomarkers for Cardiovascular Disease 
12:58 – The GameChanger 
20:37 – Connecting to Practice 
28:49 – Closing Remarks 

Host
Geoff Wall, PharmD., BCPS, FCCP, CGP
Professor of Pharmacy Practice, Drake University
Internal Medicine/Critical Care, UnityPoint Health

Guest:
Lindsay Davis, PharmD, BCPS, BCCP, TTS, ASH-CHC
Professor, Midwestern University

Lindsay Davis has no relevant financial relationships to discuss.

References and resources:

• Association of Apolipoprotein B–Containing Lipoproteins and Risk of Myocardial Infarction in Individuals With and Without Atherosclerosis Distinguishing Between Particle Concentration, Type, and Content
• AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY GUIDELINES FOR MANAGEMENT OF DYSLIPIDEMIA AND PREVENTION OF CARDIOVASCULAR DISEASE
• Primary biliary cirrhosis, hyperlipidemia, and atherosclerotic risk: a systematic review
• 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

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• CME (Physicians)

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Continuing Education Information:
Learning Objectives:
1. Describe the role of apolipoprotein B in cardiovascular management
2. Identify patients that may benefit from apolipoprotein B testing

All relevant financial relationships have been mitigated. 

0.05 CEU | 0.5 Hrs
ACPE UAN: 0107-0000-22-232-H01-P
Initial release date: 06/20/22
Expiration date: 06/20/2023
Additional CPE & CME details can be found here