GameChangers: New Guidelines for Acetaminophen Poisoning

GameChangers: New Guidelines for Acetaminophen Poisoning

N-Acetyl Cystine (NAC) has been long used as the antidose for acetaminophen poisonings – although with variable implementation. Join host, Geoff Wall, and guest, Kayla Myers, discuss a new consensus guideline for appropriate treatment of acetaminophen overdose.

THE GAMECHANGER: NAC should be used if any doubt of acetaminophen poisoning based on new consensus guidelines. NAC may be used continued beyond standard dosing for chronic or high amounts of acetaminophen.

Upon successful completion of this course, learners should be able to:
1. Apply the new modified Rumack-Matthew nomogram to a potential acetaminophen poisoning
2. Discuss the use of fomepizole in the use of acetaminophen overdose

Geoffrey C. Wall, PharmD, FCCP, BCPS, CG
Professor of Clinical Sciences
Drake University College of Pharmacy and Health Sciences

Kayla Myers, PharmD
Clinical Pharmacist
Unity Point

Dr. Wall is a member of the Janssen Speaker’s Bureau. All relevant financial relationships have been mitigated.  

Dr. Myers has no relevant financial relationships with ineligible companies to disclose. 

Course fee includes course, course materials, and CPE credit submission to CPE Monitor.
Course is non-refundable.
Release Date: September 11, 2023
Planned Expiration Date: September 11, 2024

Copyright 2023, CEimpact. All Rights Reserved. Any reproduction of this course without express permission is strictly forbidden.  

Universal Activity Number (UAN): 0107-0000-23-300-H01-P
Application-based CPE Activity

CEImpact is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. Obtain CPE credit by completing the course, followed by the exam and evaluation (if applicable). Once successfully completed, your course will appear in your Completed Courses tab. Access your CPE statement of credit at

¹CEImpact provides you with two (2) opportunities to complete the exam. The learner will not receive CPE credit after two failed attempts.

Additional information


0h 30m

Topic Designator

Disease State/Drug Therapy



ACPE Topic

01 Drug Therapy





Release Date






ACPE Number


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